Week 3

Purpose

The purpose of this video lecture is to discuss the mediator-moderator distinction, as well as review examples of empirical research on moderators and mediators in obesity research. In addition, the video lecture discusses the Craving model and Loss of Control model.

Meet the Guest Speaker

Francesca Filbey, PhD

Professor, University of Texas at Dallas

Dr. Francesca Filbey is a Professor of Cognitive Neuroscience and Director of Cognitive Neuroscience Research of Addictive Disorders at the Center for BrainHealth, School of Behavioral and Brain Sciences at The University of Texas at Dallas, and an Adjunct Associate Professor at the University of Texas Southwestern Medical School, Department of Psychiatry. She also holds the Endowed Bert Moore Chair in BrainHealth. She is the author of The Neuroscience of Addiction, as well as a co-author on an edited book and several book chapters. She is on the editorial boards of the American Journal of Drug and Alcohol Abuse and Psychology of Addictive Behaviors and has been guest editor on several journals. Dr. Filbey is an active grant reviewer for national and international funding agencies and an elected member of the American College of Neuropsychopharmacology and College on Problems of Drug Dependence.

The overarching goal of Dr. Filbey’s research is to advance the understanding of biobehavioral mechanisms related to substance use towards the goal of targeted approaches in prevention and intervention.

She incorporates translational approaches from the fields of cognitive neuroscience, neuroimaging, genetics, neuropharmacology, psychology, and psychiatry to understand the antecedents and consequences of substance use.

Video Lecture

The video lecture is broken into four parts: Brief overview, examples of empirical research, craving, and loss of control.

Please click each tab to watch each part of the video lecture.

Brief Overview
Examples of Empirical Research
Craving
Loss of Control

Brief Overview

Examples of Empirical Research

Craving

Loss of Control

Accessibility Note: To access auto closed captions (CC) services please click on the icon in the video's bottom right corner. Manual CC are available by submitting a request for services to ATAC: (812) 856-4112 or atac@iu.edu

NOTE: Please click on the links below to download the video lecture slides:

Conceptual Models of Mediating and Moderating Variables of Obesity

Readings

Below are suggested readings that may be of interest for you:

Filbey, F. M. and U. S. Yezhuvath (2017). "A multimodal study of impulsivity and body weight: Integrating behavioral, cognitive, and neuroimaging approaches." Obesity (Silver Spring) 25(1): 147-154. https://doi.org/10.1002/oby.21713
Feldstein Ewing, S. W., et al. (2017). "Overweight adolescents' brain response to sweetened beverages mirrors addiction pathways." Brain Imaging Behav 11(4): 925-935. https://doi.org/10.1007/s11682-016-9564-z
Filbey, F. M., et al. (2012). "Reward circuit function in high BMI individuals with compulsive overeating: similarities with addiction." Neuroimage 63(4): 1800-1806. https://doi.org/10.1016/j.neuroimage.2012.08.073
Filbey, F.M. (2019). Neuroscience of Addiction. Cambridge University Press.