Course Syllabus

SPH-K 543: Cortical Control Of Human Movement

Many areas of the brain contribute to the control of movement. Through lectures and discussions of primary literature, this course will examine our current understanding of the cortical and sub-cortical motor structures of the brain. The student will learn the anatomy and physiology of these structures, their contributions to motor control, and the movement deficits that result from stroke or trauma to these regions. We will cover the primary motor cortex, premotor cortex, supplementary motor area, cerebellum, and basal ganglia, and we will discuss posterior parietal cortex and the role of sensory information and neural networks in motor control. We will also do a short writing assignment that students will submit to Neuro Forum, a publication of the Journal of Neurophysiology.

Competencies

 

The student will:

  • gain detailed knowledge of the behavioral and physiological functions of the motor structures in the human brain
  • become familiar with the deficits that result from disease or injury to motor structures of the brain
  • develop his or her ability to read, discuss, and present papers from the primary literature
  • learn about the publication process, including peer review and revisions.

Course instructor

Hannah Block, Ph.D.

E-mail:   hjblock@indiana.edu

Phone:   812-855-5390

Office:   SPH 176

Associate Instructor

Yang Liu

E-mail: YL82@indiana.edu

Office hours

By appointment

Meeting times

Tuesdays and Thursdays

2:30-3:45pm

Classroom

GY 407

 

Class schedule (subject to change):

Date

Topic

Required reading,

Suggested background reading

Deadlines

Tuesday, Aug. 25

Introduction

 

 

Thursday, Aug. 27

Background

Kandel ch. 17-18, 33

 

Tuesday, Sept. 1

M1 lecture

Kandel ch. 38

 

Thursday, Sept. 3

TMS methods

Hallett 2007

 

Tuesday, Sept. 8

Paper 1/fMRI methods

Classen et al. 1998: HB

 

Thursday, Sept. 10

Paper 2

Volz et al. 2015: Jasmine

 

Tuesday, Sept. 15

PMv lecture

Kandel ch. 38

 

Thursday, Sept. 17

PMd/SMA lecture

Kandel ch. 38

 

Tuesday, Sept. 22

Paper 3

Graziano et al. 2002: Brandon

 

Thursday, Sept. 24

Clinical topic: stroke

n/a

 

Tuesday, Sept. 29

Cerebellum lecture

Kandel ch. 42

 

Thursday, Oct. 1

QUIZ 1 (up to Sept. 24)

 

 

Tuesday, Oct. 6

Paper 4

Cantarero et al. 2015: Boxuan

 

Thursday, Oct. 8

Basal Ganglia lecture

Kandel ch. 43

 

Tuesday, Oct. 13

Clinical topic: HD (Alan Phipps)

n/a

 

Thursday, Oct. 15

Paper 5

Chen et al. 2014: Stephanie

 

Tuesday, Oct. 20

SfN—no class

n/a

 

Thursday, Oct. 22

PPC

Grefkes et al. 2005

 

Tuesday, Oct. 27

Sensorimotor learning

Bays & Wolpert 2007, Proske & Gandevia 2012

 

Thursday, Oct. 29

MINI REVIEW TOPIC DISCUSSION

 

Mini review topic due 2:30pm

Tuesday, Nov. 3

Paper 6

Bufalari et al. 2014: Brandon

 

Thursday, Nov. 5

QUIZ 2 (Sept. 29-Oct. 27)

 

 

Tuesday, Nov. 10

Paper 7

Wu et al. 2014: Boxuan

 

Thursday, Nov. 12

Paper 8

Marini et al. 2014: Chuyi

Mini review 1st draft due 2:30pm.

Tuesday, Nov. 17

MINI REVIEW DISCUSSION

 

Peer reviews of first drafts due 2:30pm

Thursday, Nov. 19

MINI REVIEW DISCUSSION

 

 

Tuesday, Nov. 24

Thanksgiving—no class

n/a

 

Thursday, Nov. 26

Thanksgiving—no class

n/a

 

Tuesday, Dec. 1

Paper 9

Koch et al. 2008: Stephanie

 

Thursday, Dec. 3

Paper 10

Zenon et al. 2015: Chuyi

Revised mini review due, 2:30pm

Tuesday, Dec. 8

Paper 11

Kishore et al. 2014: Jasmine

 

Thursday, Dec. 10

MINI REVIEW DISCUSSION

 

Peer reviews of revisions due 2:30pm

Friday,

Dec. 17

 

 

Submit your mini review to journal by 11:59pm.

All required and optional readings will be provided in the appropriate module on the Canvas site for this course.  PowerPoint slides for each lecture will also be provided, usually the afternoon before the lecture.

 

Grade

Grades will be assigned according to the following: 93-100% A; 90-93% A-; 87-90% B+; 83-87% B; 80-83% B-; 77-80% C+; 73-77% C; 70-73% C-; 67-70% D+; 63-67%D; 60-63% D-; <60% F

20% Participation1

20% Presentations2

30% Quizzes (15% each)

30% Mini review3 (10% your mini review first draft, 10% your revised mini review, and 10% peer review)

 

1 Even if not presenting the paper, each student is expected to participate (voluntarily or as called upon by the instructor) in the classes in which we discuss a paper. Attendance and participation in the paper discussion classes are required and will count toward your participation grade. The instructor will give each student (who is not presenting) a 0 or 1 each time. A student who is absent, does not participate, or has clearly not read the paper will receive a 0.

 

2 Each student will present 2 of the 11 papers and guide the discussion on those two days. The presentation should include slides and should cover:

  • background
  • overview of method, results, and authors’ conclusions
  • criticisms or weaknesses of the methods, results, or conclusions
  • significance or importance of the paper

Detailed guidelines for the presentations are listed in the Resources folder of the course website.

 

3 Each student will write a mini review (2300 words max) of a current topic in motor control neuroscience. Students will choose their own topics, subject to the instructor’s approval. After the mini review first drafts are due, peer reviewers will be assigned. Each student will then revise their mini review according to the class’s suggestions, after which a second round of peer review will occur.   Finally, each student is required to submit their work to Neuro Forum, which is a publication of the Journal of Neurophysiology intended for graduate students and postdocs: http://www.the-aps.org/mm/Publications/Journals/JN/Neuro-Forum-Guidelines.html Links to an external site., or to another journal. This is a great opportunity to get a peer-reviewed publication early in your graduate career, and a chance for the whole class to experience the review and publication process.

 

Mini review deadlines

  • 29, 2:30pm—Mini Review topic due.  You must come to class prepared to discuss and justify your chosen topic.
  • 12, 2:30pm—Mini Review first draft due.  Upload on Canvas.
  • 17, 2:30pm—First round of peer reviews due.  You will be assigned other students’ work to critique.  Fill out a peer review form for each mini review you critique and be prepared to discuss them in class.
  • 3, 2:30pm--Revised Mini Review due.  Upload on Canvas.
  • 10, 2:30pm--Second round of peer reviews due.  You will be assigned other students’ work to critique.  Fill out a form (to be provided by Nov. 17) for each mini review you critique and be prepared to discuss them in class.
  • 17, 11:59pm—To receive a final grade for this assignment, you are required to do a final revision if needed and submit your mini review to Neuro Forum or another appropriate publication.  Forward me the e-mail confirmation of your submission.  Here are instructions on submitting to Neuro Forum: Neuro Forum submission.pptx

 

Late assignments policy

Assignments up to 24 hours late will receive up to half credit (i.e., if your score is 90/100, you will receive only 45). Assignments more than 24 hours late will receive a zero.

 

Course policies and procedures

1) Attendance will be taken at the instructor’s discretion. Various assignments will be given periodically in lecture. Make-ups will not be allowed for those assignments missed due to absence.

2) Make-up exams may only be scheduled if: an arrangement is made prior to the exam with the instructor’s permission; or a valid medical excuse is presented to the instructor within one week of the exam.

3) A grade of incomplete (I) will only be given in emergency circumstances (e.g., illness).

4) Academic and personal misconduct by students in this class are defined and dealt with according to the procedures in the Code of Student Ethics.

5) It is the policy of the School of Public Health to evaluate all courses taught in the School. Final student course evaluations will be conducted in a manner that maintains the integrity of the process and the anonymity of the evaluators.

 

 

Course Summary:

Date Details Due